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Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIAA1704
All Species:
35.76
Human Site:
S275
Identified Species:
65.56
UniProt:
Q8IXQ4
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXQ4
NP_061029.2
340
38142
S275
N
E
S
K
R
S
E
S
L
M
D
I
H
H
K
Chimpanzee
Pan troglodytes
XP_509661
340
38139
S275
N
E
S
K
R
S
E
S
L
M
D
I
H
H
K
Rhesus Macaque
Macaca mulatta
XP_001094145
344
38614
S279
N
E
S
K
R
S
E
S
L
M
D
M
H
H
K
Dog
Lupus familis
XP_851499
342
38712
S277
N
E
S
K
R
S
E
S
L
M
D
I
H
H
K
Cat
Felis silvestris
Mouse
Mus musculus
Q69ZC8
346
38936
S281
N
E
S
K
R
S
E
S
L
M
D
I
H
H
K
Rat
Rattus norvegicus
Q4V893
348
39156
S283
N
E
S
K
R
S
E
S
L
M
D
I
H
H
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514535
347
38704
S282
N
D
S
K
R
S
E
S
L
M
D
I
H
H
K
Chicken
Gallus gallus
NP_001006270
350
39239
S285
N
E
S
K
R
S
E
S
L
M
D
I
H
Q
K
Frog
Xenopus laevis
NP_001089474
337
37926
S272
N
D
S
R
R
S
E
S
L
I
D
L
H
R
K
Zebra Danio
Brachydanio rerio
NP_001003473
405
45367
E339
Y
N
E
S
K
R
G
E
S
L
I
S
L
H
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_996214
349
39457
L288
V
E
L
H
Q
K
K
L
R
K
E
Q
R
E
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q93591
297
33204
V245
Q
K
K
R
D
E
K
V
K
D
A
G
Y
A
Q
Sea Urchin
Strong. purpuratus
XP_796639
403
45460
K329
R
L
A
D
M
V
A
K
H
N
E
T
K
R
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.3
91.5
N.A.
89.5
87.3
N.A.
64.2
68.8
63.2
47.1
N.A.
26.9
N.A.
27.6
37.9
Protein Similarity:
100
100
98.5
96.1
N.A.
93.6
93.3
N.A.
75.2
80
75.8
60.2
N.A.
41.5
N.A.
44.7
53.8
P-Site Identity:
100
100
93.3
100
N.A.
100
100
N.A.
93.3
93.3
66.6
6.6
N.A.
13.3
N.A.
0
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
93.3
20
N.A.
33.3
N.A.
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
8
0
0
0
8
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
16
0
8
8
0
0
0
0
8
70
0
0
0
0
% D
% Glu:
0
62
8
0
0
8
70
8
0
0
16
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
8
0
0
0
70
62
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
8
54
0
0
0
% I
% Lys:
0
8
8
62
8
8
16
8
8
8
0
0
8
0
77
% K
% Leu:
0
8
8
0
0
0
0
8
70
8
0
8
8
0
0
% L
% Met:
0
0
0
0
8
0
0
0
0
62
0
8
0
0
0
% M
% Asn:
70
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
8
0
0
0
0
0
0
8
0
8
8
% Q
% Arg:
8
0
0
16
70
8
0
0
8
0
0
0
8
16
0
% R
% Ser:
0
0
70
8
0
70
0
70
8
0
0
8
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% T
% Val:
8
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _